Dans le cadre d’un vaste effort multi-institutionnel dirigé par l’Université de Californie à San Diego, des chercheurs ont analysé plus d’un million de cellules cérébrales humaines pour produire des cartes détaillées des commutateurs génétiques dans les types de cellules cérébrales et ont révélé les liens entre des types spécifiques de […]
According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd — but very important — to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha (RARα), is known to control gene expression programs in the nucleus, […]
Logan Paul is mostly focused on his October return to the boxing ring, but coming off his victory over Ricochet at SummerSlam he seems to still has the pro wrestling ring on his mind. At least based on the latest episode of Impaulsive, where the Media Megastar was brainstorming his […]
The precise segregation of DNA and the faithful inheritance of plasmids are crucial steps in bacterial cell division. Now, a team of researchers led by Seán Murray at the Max Planck Institute for Terrestrial Microbiology has developed a computational simulation that explains a key mechanism of DNA segregation. Their findings […]
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have uncovered new molecular targets on a cell receptor that play a major role in cardiovascular regulation. The findings could lead […]
Atherosclerosis is a disease in which fat, cholesterol, and other substances build up inside artery walls. This can lead to plaque formation, which can block arteries and cause heart attacks and strokes. Immune cells play a key role in cleaning the blood, by interacting with red blood cell extracellular vesicles […]
The researchers also identified three proteins that are needed for the virus to carry out the invasion and have in turn synthesized molecules (potential drugs) that can target one of the proteins, potentially leading to new treatments for AIDS. « We have revealed a protein pathway that appears to have a […]
In the ongoing search for a cure for Alzheimer’s disease, a burgeoning branch of medicine is bringing new hope. Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system. In a new proof-of-concept study, scientists at University of California San Diego […]
Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the activation occurs, from cells and molecules to other components in the so-called tissue microenvironment. Now, an interdisciplinary Cornell team […]
Immune system T cells that should be able to kill cancer cells become dysfunctional or « exhausted » within hours of encountering a tumor, according to a study reported Aug. 3 in Nature Immunology. The surprising findings have implications for cancer immunotherapies that aim to harness the tumor-killing power of T cells, […]
